SANTA CLARA -- The 49ers just lost 40-34 to the Detroit Lions. Here are the 49ers' grades for this emabarrassing performance. Brock Purdy was an extreme version of the quarterback he has been all ...

The 49ers are riding a tow game losing streak into Week 17. They are poised to increase it to three in their matchup with the Lions. Here are three reasons why the 49ers will lose to the Lions.

Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season Click to share on Facebook (Opens in new window) Click to share on Twitter ...

The last time the 49ers hosted the Detroit Lions, the stakes could hardly be higher. It was the NFC title game, and the 49ers came back from a 17-point halftime deficit to win, 34-31, and advance ...

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

The Detroit Lions probably didn’t have to play their starters on Monday night, but did, and the blueprint for the rest of their season became clearer. The Lions can score a lot of points.

Lions 40, 49ers 34, final: The 49ers score a touchdown but can’t recover the onside kick as the Lions hold on for their 14th win of the season. Jared Goff threw for 300 yards, Jahyr Gibbs ran ...

So, it’s come to this: no matter what the Detroit Lions do on Monday night in Week 17 against the San Francisco 49ers, they’ll be playing for the NFC North title against the Minnesota Vikings ...

The San Francisco 49ers and Arizona Cardinals play on Sunday, Jan. 5 at the Cardinals' State Farm Stadium in a game on the NFL Week 18 schedule. Which team will win the NFL Week 18 game?

Brock Purdy threw for a career-high 377 yards and three touchdowns as the San Francisco 49ers fell to the Detroit Lions 40-34 at Levi's Stadium on Monday Night Football. Purdy also threw two ...