New work by Columbia researchers has turned a textbook principle of genetics on its head and revealed why some people who ...

Mitochondria are vital to energy production in cells and so play a key role in fueling cancer growth. However, how ...

The discovery could help explain why some cancer patients respond well to certain treatments, while others are not so lucky.

He explores how flaws in the transcription and DNA repair pathways contribute to cancer predisposition and accelerated aging ...

Researchers unveil histone-based age predictors, offering a new window into epigenetic aging and its shared patterns across ...

A new study has uncovered how the defense mechanisms of bacteria can be neutralized, facilitating more efficient genetic ...

A new study by Tel Aviv University reveals how bacterial defense mechanisms can be neutralized, enabling the efficient ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

A new priority research paper, featured as the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22, was published on December 29, 2024 ...

Biological age refers to how old a person’s body is biologically, which may differ from their actual age in years.

By inhibiting the DNA polymerases, BKC enhances the endogenous RS in cancer cells, leading to increased DNA damage. IBC specifically inhibits CHK2 to prevent DNA repair. The combined use of BKC and ...