Jim FessendenUMass Chan Medical SchoolNew research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

UMass Chan scientists discover process controlling cilia development Work by Sumeda Nandadasa and colleagues uncovers a molecular mechanism affecting ciliopathies such as Meckel-Gruber and Joubert ...

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

But there is still a lot we don't know about cilia in many cell types, such as neurons or cancer cells. Scientists have learned, however, that cilia may be critical to the growth of some cancers, and ...

Cilia drive fluid flow in development and physiology, but this requires that all cilia in a tissue orient the same way. Earlier studies indicated that both planar cell polarity (PCP) signalling ...

Cilia are outgrowths of the plasma membrane of eukaryotic cells that contain a specialised cytoskeleton. Motile cilia are present on multiciliated cells and use this cytoskeleton to move fluid ...

Patient #7: 15 cells with profiles, 0 cells with normal cilia, 0 cells with abnormal cilia. Taken together, only one patient expressed morphologically normal cilia.

Human Cilia Disease Cilia are ubiquitous hair-like organelles that form specialised cell compartments, extending out from the surface of most cells in the body with an internal microtubular axoneme ...