The current study shows that cells with additional chromosomes have an altered mitochondrial structure and function. The reason: mitochondrial precursor proteins are sequestered in p62-positive ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Cancer cells with extra chromosomes depend on those chromosomes for tumor growth, a new Yale study reveals, and eliminating them prevents the cells from forming tumors. The findings, said the ...

Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply—and can contribute to ...

DigC Is Designed to Analyze CNV in a Single Cell The analysis of copy numbers of genetic sequences is of fundamental importance in biology and medicine, and Digital Counting (DigC) is a new method to ...

ChromTR, a cutting-edge framework for chromosome detection in metaphase cell images, represents a significant advancement in the field of cytogenetics. This framework, which integrates semantic ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can ...