Human egg cells are often prone to chromosomal errors. As women age, the error rate increases sharply—and can contribute to ...

The Cohesin complex is placed at the heart of many DNA-based processes including sister chromatid cohesion and chromatin loop extrusion. The Cohesin release factor Wapl opens the DNA exit gate in ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Sister-chromatid cohesion mediated by the ...

THE induction of chromosomal aberrations by exogenous agents, such as viruses, radiation and chemicals, is an area of active cytogenetic investigation. 1 Recently, the psychotomimetic hallucinogen, ...

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Abstract: To evaluate the function of cohesin and its regulators, classifications of chromosomes based on the positional relationship between sister chromatids are used. Although the analysis has been ...

Human chromosomes (human normal karyotype). Humans have 23 pairs of chromosomes, with one set inherited from each parent. The main difference between the karyotype of a female and a male lies in the ...

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural network (CNN) with ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural ...

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