Researchers have developed lipid nanoparticles (LNPs) that cross the blood-brain barrier (BBB) and precisely target brain cells, a major step toward treating neurological diseases like Alzheimer’s.

Electroporation works well with cell lines that are refractive to other techniques, such as calcium phosphate–DNA coprecipitation. But as with other transfection methods, the optimal conditions ...

In this manuscript, Yao et al. present solid evidence to show that MnMYL3 may serve as a receptor for NNV via macropinocytosis. This manuscript is valuable for understanding the molecular mechanisms ...

as well as a positive control non-cancerous cell line with very high transfection rate. In all the above cell lines, Smart mRNAs were successfully turned off when the corresponding genetic signature ...

Company aligned with FDA on CMC strategy and requirements in preparation of Phase 3 pivotal trial of IMNN-001Vertical integration of major ...

CellFE®, a disruptive life sciences company marketing non-viral, non-electroporative cell therapy manufacturing tools, today announced several strategic system placements with major pharmaceutical and ...

However, our understanding of how gradual changes in gene dosage affect molecular, cellular, and organismal traits is currently limited. To address this gap, we induced gradual changes in gene ...

Merck, a leading science and technology company, has signed a definitive agreement with the intention to acquire HUB ...

What does it take to design a new needle for medical use? When the needle needs to be much thinner and sharper than any ...

Recombinant antibody technology has helped address many problems associated with hybridoma platforms, opening the door to a ...