Follow along with score and in-game updates as the Bills host the Patriots on Sunday afternoon at Highmark Stadium.

The Buffalo Bills were handed a potentially huge edge over the Kansas City Chiefs in the race for the No. 1 seed in the AFC ...

The Lions, Bills and Eagles form a top tier in odds to win the Super Bowl with the Chiefs out of the top two for the first ...

The Buffalo Bills played in another high-scoring thriller, Patrick Mahomes picked up a worrying injury and three teams booked ...

Buffalo will need help to capture the No. 1 overall seed, but it is possible. The Bills hold the head-to-head tiebreaker over ...

NFL fans can feel it in their bones: this is the Buffalo Bills’ best chance of a Super Bowl winner in over 30 years. Fresh ...

The Patriots face the Bills in Buffalo on Sunday. We break down what the game means for the NFL playoff picture.

While the Bills and the Chiefs are fierce conference rivals, Mahomes' wife, Brittany Mahomes remains best friends with Paige ...

Regardless of what time they're expected to face off, the Buffalo Bills will host the New England Patriots in Week 16. The Bills-Patriots clash was flexed from ...

Buffalo travels to New England at 4:25 p.m. Sunday but the other games of interest for the Bills kick off Saturday. The four ...

It's Buffalo Bills vs New England Patriots in Week 16 of the NFL season. Can Josh Allen and James Cook keep it rolling ...

The Buffalo Bills face the less-fancied New England Patriots, but there's a lot at stake for Sean McDermott's team.