The Buffalo Bills were short on defense due to injuries, but one of their Day 3 draft selections stepped up and was named among the NFL’s biggest winners

Ticket prices for the Bills vs Patriot in Week 5 start at $280 on Vivid Seats and $269 on StubHub. Prices in the lower bowl range from $291 to $547 on both sites. Here is the entire 2025 Buffalo Bills schedule.

NFL Week 5 odds, picks, predictions, TV channel, streaming information for Sunday Night Football game between New England Patriots and Buffalo Bills.

Buffalo Bills punter Cameron Johnston suffered a leg injury in the Week 4 win over the New Orleans Saints and the latest injury update on the veteran is not good.

For the Patriots (2-2), the Bills represent a terrific opportunity to measure themselves against one of the best rosters in football.

Alone and on top of the AFC Conference standings, the Buffalo Bills (4-0) have put up 30 points in every game this year. They've done what they've needed to do to win.

Wegmans is going beyond the freezer aisle for the big game. The grocer is also selling limited-edition Buffalo Bills Rivalries long-sleeve white T-shirts, designed exclusively for the supermarket chain. Bills Mafia, known as one of the NFL’s most passionate fan bases, is encouraged to wear them on Sunday to help white-out Highmark Stadium.

It was not his prettiest win as a head coach but Sean McDermott joined the ranks of some of the NFL’s best coaches in league history after the Buffalo Bills defeated the New Orleans Saints 31-19 in Week 4.