The San Francisco 49ers might have a new face at linebacker when they visit the Indianapolis Colts in Week 16.

San Francisco 49ers wide receiver Ricky Pearsall has missed the team's first practice of the week due to knee and ankle injuries.

Colts’ Jonathan Taylor; Ricky Pearsall Jr. doesn’t practice but Kyle Shanahan likes his chances to play Monday.

The San Francisco 49ers defense has been surviving despite injuries, and a lot of that credit has been given to Robert Saleh. Saleh was always expected to use the 49ers as a pit stop to regain his strong reputation as a head coaching candidate and parlay this into a new job.

The Indianapolis Colts and San Francisco 49ers understand the stakes Monday night. Both teams find themselves in the throes of tight division races where one more loss could eliminate them.

Meanwhile, the 49ers are set to get some much-needed reinforcements on run defense, and Ricky Pearsall's status for Week 16 is unclear.

Speaking with PEOPLE, the soon-to-be mom of two, who recently partnered with Pampers on one of their diapers, shares how her fellow WAGs have become part of her community.

The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the team’s fourth win in a row.