San Francisco 49ers QB Brock Purdy connects with WR Ricky Pearsall on a 3-yard pass who laterals to RB Christian McCaffrey for an additional 20 yards.

Jaguars QB Trevor Lawrence, LB Devin Lloyd and DT Arik Armstead speak with the media after the 26-21 win over the San Francisco 49ers in Week 4 of the 2025 NFL Season.

Fresh off a grind-it-out win over the Houston Texans, the Jacksonville Jaguars (2-1) are preparing for a tilt Sunday against the San Francisco 49ers (3-0) in Northern California.

Heading into the week, the 49ers got a minor scare when Ricky Pearsall did not practice because of knee soreness stemming from the team’s Week 3 win over the Arizona Cardinals. Pearsall was quite active in that game,

Watch highlights from the Week 4 matchup between the Jacksonville Jaguars and the San Francisco 49ers during the 2025 NFL season.