QB Brock Purdy faces elbow injury scare in loss to Lions, but initial tests show no damage to surgically repaired UCL.

Rams coach Sean McVay opts to rest Matthew Stafford, giving Jimmy Garoppolo his first start with the team against Seattle.

San Francisco 49ers quarterback Brock Purdy reportedly suffered a nerve issue in his right elbow late in Monday's 40-34 loss against the Detroit Lions and will undergo further testing on Tuesday ...

The 49ers are riding a tow game losing streak into Week 17. They are poised to increase it to three in their matchup with the Lions. Here are three reasons why the 49ers will lose to the Lions.

Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season Click to share on Facebook (Opens in new window) Click to share on Twitter ...

The 49ers will be down another key starter against the Lions on Monday night. All-Pro cornerback Charvarius Ward will not be active when the 49ers take on the Lions. He is out with a "personal ...

The Detroit Lions probably didn’t have to play their starters on Monday night, but did, and the blueprint for the rest of their season became clearer. The Lions can score a lot of points.

The Detroit Lions scored on five consecutive drives in the second half to pull away for a 40-34 win over the host San Francisco 49ers on the final "Monday Night Football" matchup of the season.

Either way, we’ll likely hear their names often on Monday Night Football, as one of those newcomers will be protecting 49ers’ quarterback Brock Purdy’s blindside against the Lions.

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN's Adam Schefter. More news: Titans Reveal RB Tony Pollard's Playing ...