The Arizona Cardinals and San Francisco wrap up their NFL seasons with a Week 18 game between old rivals. Here's what to know and how to watch.

The Cardinals are 1-5 since the bye week but have a chance to finish strong against the 49ers on Sunday afternoon in Glendale ...

In the final game of Week 17, the San Francisco 49ers will play host to the Detroit Lions on "Monday Night Football." San ...

The 49ers just lost 40-34 to the Detroit Lions. Here are the 49ers' grades for this emabarrassing performance. QUARTERBACK: C ...

SF 49ers coach Kyle Shanahan, quarterback Brock Purdy, lineman Nick Bosa, linebacker Fred Warner speak after loss to Lions ...

WR Ricky Pearsall reflects on surviving a shooting during a robbery attempt, expressing gratitude for the support that aided his recovery.

Detroit’s advantages even extend to the specialists, where Jack Fox surpasses Pat O’Donnell and young Jake Bates has proven ...

Welcome to the Week 17 grades! There's always a lot of drama in the NFL over the final two weeks of the season, and that was ...

Sanders makes fifth field goal of the day, Dolphins take a 22-17 lead Another ... Miami Dolphins vs. San Francisco 49ers ...

The Detroit Lions have a short week to prepare for a pivotal matchup against Minnesota, and they will not complain about that ...

The bad injury situation exacerbated for the 49ers during the week with multiple downgrades – Colton McKivitz, Charvarius ...

The Detroit Lions (13-2 SU, 10-5 ATS) hit the road to face the San Francisco 49ers (6-9 SU, 5-10 ATS) to close the NFL Week ...