Lisa Murkowski said Thursday she will vote against Secretary of Defense nominee Pete Hegseth, who is facing a barrage of accusations about his personal conduct, making the Alaska Republican the first in her party to oppose one of President Donald Trump’s cabinet picks.

The Alaska Republican’s decision Thursday comes ahead of a crucial test vote to advance Hegseth’s nomination toward confirmation.

A defining duo of the first Donald Trump administration is back.

The Senate voted largely along party lines Thursday to advance Pete Hegseth, President Trump’s nominee to serve as secretary of Defense, brushing aside a litany of misconduct allegations and the objections of Democrats who argued he is unqualified for the job.

Two Republican senators publicly announced they would vote against the confirmation of Pete Hegseth, President Donald Trump’s cabinet pick for defense secretary.

The Alaska Republican plans to vote against the confirmation of Pete Hegseth to lead the Department of Defense.

Alaska Senator Lisa Murkowski announced that she would not back President Donald Trump’s controversial Pentagon nominee, and Maine Senator Susan Collins has also voiced her disapproval.

Republicans say they are confident that Hegseth, who has been accused of alcohol and domestic abuse, will ultimately be confirmed to lead the Pentagon.

GOP Sen. Lisa Murkowski says she "cannot in good conscience" support Pete Hegseth for secretary of defense, and she and Sen. Susan Collins voted "no" on his nomination in a procedural vote.

Sen. Lisa Murkowski announced Thursday that she would vote against confirming Pete Hegseth to lead the Pentagon, becoming the first Republican to oppose one of President Donald Trump’s Cabinet picks. Maine GOP Sen. Susan Collins also voted against Hegseth.

Two Republican Senators, including Maine’s Susan Collins, voted against the confirmation of Pete Hegseth as President Donald Trump’s defense secretary.

WASHINGTON—Two centrist Republican senators said they opposed the nomination of President Trump’s defense-secretary pick, Pete Hegseth, injecting new drama into what was expected to be a nail-biter of a vote Friday.