Rams dominated early, 49ers stumbled with turnovers. Despite offensive flashes, defensive lapses proved too costly in a decisive divisional loss.

He’s been as relentlessly positive as ever, cracking up teammates while at the same time inspiring them to do greater things. It’s no accident the 49ers’ two best rushing games against Atlanta and the New York Giants came with Kittle delivering key blocks and setting a physical tone.

Davante Adams played a key role in the Los Angeles Rams ’ 42-26 blowout win over the San Francisco 49ers on Sunday. The three-time All-Pro wide receiver registered six receptions for 77 yards (both team-highs) and one touchdown.

It wasn’t nearly enough with the Rams making significantly more plays on offense and defense to avenge their Week 5 loss against their rival. Which plays sealed the deal? Here were the 5 game-defining plays in Los Angeles’s Week 10 win.

Tom Brady awards Los Angeles Rams QB Matthew Stafford with the LFG Player of the Game after his four touchdown performance against the San Francisco 49ers.

The Los Angeles Rams scored touchdowns on their first three drives, and the San Francisco 49ers never were able to dig themselves out of that hole.

The Los Angeles Rams knew that they would play Mac Jones on Sunday after the San Francisco 49ers made that announcement earlier this week. Jones, who has been dealing with an injury while playing throughout the entire season, enters Sunday's contest with an issue with his knees.

Find out how to watch the NFL Week 10 game between the Los Angeles Rams and San Francisco 49ers, as well as the latest odds and updated injury report.