GLENDALE -- The Arizona Cardinals ended their regular season on a high note with a 47-24 win over the San Francisco 49ers in Week 18 ... straight touchdown between SF/AZ was scored to start ...

The San Francisco 49ers and head coach Kyle Shanahan today announced that Robert Saleh has been named as the team’s defensive ...

(AP) The Cardinals' final passing touchdown of ... quarter that sealed their 47-24 win over the San Francisco 49ers on Sunday. Arizona hopes that's just a preview of what's coming next season.

As the offseason unfolds, all eyes will be Brock Purdy's contract negotiations and the future of the San Francisco 49ers.

Kyler Murray tied a career high with four touchdown passes and did not throw an interception Sunday to lead the Arizona Cardinals to a 47-24 victory and season sweep of the San Francisco 49ers at ...

The San Francisco 49ers will be active during NFL free agency in March. Here, we look at five early options for the team.

Out of the postseason race, the San Francisco 49ers and Arizona Cardinals are preparing to start backups because of injuries for their season-ending matchup Sunday in Glendale, Ariz. San Francisco ...

The 49ers had the NFL's second-highest-graded receiver duo in George Kittle and Jauan Jennings according to Pro ...

The San Francisco 49ers could turn to a Bay Area native as their defensive coordinator for the 2025 season and beyond.