A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Genetic variants believed to cause blindness in nearly everyone who carries them actually lead to vision loss less than 30% ...

Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of ...

A man sits outside and holds a slim menthol cigarette between his fingers. Close-up with focus on the cigarette. The study provided a comprehensive examination of how lifestyle and environmental ...

Human cells usually contain two copies of most genes, one of which comes from the mother while the other comes from the father. It's long been thought that usually these two copies, or alleles of ...

A rare form of diabetes affecting newborn babies and caused by a genetic disorder has been discovered by scientists in the UK ...

A study published in Nature Genetics reveals new insights into how medulloblastoma, the most common malignant brain tumor of childhood, can arise as the cerebellum develops. Researchers discovered ...

Two of Opus's seven gene therapy assets are in clinical trials, with additional programs expected to enter the clinic.