Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing ...
Pranam Chatterjee, PhD, assistant professor of bioengineering at the University of Pennsylvania (UPenn), emphasizes that text is all you need for artificial intelligence (AI) models to effectively ...
Designing drugs is a bit like playing with Polly Pocket. The vintage toy is a plastic clam shell that contains a multi-bedroom house, a skating rink, a disco dance floor, and other fun scenarios. Kids ...
Researchers from Canada and the United States have created an artificial intelligence (AI) tool called PepMLM to target “undruggable” disease proteins. This development could lead to new treatments ...
Discover how researchers are overcoming the limitations of the undruggable target in drug discovery using novel approaches ...
A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle ...
Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and ...
Targeted protein degradation has moved well beyond its prologue more than 20 years ago. 1 The number of publications describing different PROTACs (PROteolysis TArgeting Chimeras), molecular glues, and ...
A three-decade-old competition that has spawned three Nobel laureates is becoming victim to the chaos at the National Institutes of Health. The Community Wide Experiment on the Critical Assessment of ...
Astronomers use the term dark energy to refer to energy in the universe that is unaccounted for by ordinary matter but ...