Researchers have found, for the first time, that a blood-clotting protein can, unexpectedly, degrade nerves--and how nerve-supporting glial cells, including Schwann cells, provide protection. The ...

A study maps how toxic tau disrupts synapses over time, showing early postsynaptic damage that later spreads presynaptically.

Co-written with Jai Liester. Silent synapses represent one of neuroscience's most fascinating discoveries—connections between neurons that lie dormant until activated by specific triggers. These ...

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Leptin is a hormone released by fat cells in adult organisms, and researchers have largely focused on how it controls appetite. In a study published May 18 in Science Signaling, the authors show that ...

Scientists from Oregon Health & Science University (OHSU) and the University of Edinburgh have discovered that a little-understood junction that connects neurons to oligodendrocyte precursor cells ...

For more than a century, the story of the brain has been told as a tale of neurons, with every thought and memory traced to their electrical chatter. That narrative is now being rewritten as evidence ...

Researchers headed by a team at the University of Texas at Dallas’ Center for Advanced Pain Studies (CAPS) have made a fundamental discovery about a key mechanism that enables nervous system ...

Scientists at Yale and the University of Connecticut have taken a major step in understanding how animal brains make decisions, revealing a crucial role for electrical synapses in “filtering” sensory ...

Processing of sensory impressions and information depends very much on how the synapses in our brain work. A team has now shown how lipid and protein regulation impact brain's processing of a ...