Muscle-derived branched-chain amino acids support thermogenesis in brown adipose tissue, thereby helping maintain body temperature during impaired muscle function or physiological stress.

A. Fluorescent immunostaining of PDGFRα, showing mesenchymal progenitors, laminin surrounding skeletal muscle, and AR. Arrows indicate mesenchymal progenitors expressing AR, arrowheads indicate ...

The results of studies in mice suggest that vitamin D deficiency may impair muscle mitochondrial function, impacting on energy production in muscle cells and so potentially affecting muscle ...

If lifespan is about how long you live, and healthspan is about how long you live in good health, then musclespan is the ...

A decline in metabolism and endurance of skeletal muscle is commonly observed in obese patients, but the underlying mechanism is not well-understood. A research team led by Dr Chi Bun CHAN, Assistant ...

Tissue-resident macrophages can originate from embryonic or adult hematopoiesis. They play important roles in a wide range of biological processes including tissue remodeling during organogenesis, ...

The effect of iron supplementation on skeletal muscle atrophy in cancer patients and sufferers from other wasting diseases has been investigated by scientists who studied causes of these conditions in ...

Scientists have produced a comprehensive roadmap of muscle aging in mice that could be used to find treatments that prevent decline in muscle mobility and function. Scientists have produced a ...

A University of Alberta research team is shedding much-needed light on cancer cachexia, a severe muscle-wasting syndrome ...