For decades, the idea that the human brain might naturally produce the psychedelic compound DMT has attracted considerable attention. It has been speculated that DMT could function as a natural ...

A new study finds no evidence of naturally occurring DMT or its storage in the serotonin neurons of the rat brain.

The full project took seven years, beginning when Roth’s lab solved the complex chemical structure of serotonin receptors, including what they look like when a psychedelic compound is tightly bound to ...

Ithaca, NY - Rates of anxiety and depression have been increasing around the world for decades, a trend that has been sharply exacerbated by the COVID-19 pandemic. New research led by the Boyce ...

Classical psychedelics act on a surprisingly broad range of brain receptors, not just the serotonin receptor long associated with their hallucinogenic effects, according to new research published in ...

A major paper debunking the “serotonin hypothesis” has a lot of people agitated. But leaving more room for nuance in our discussions about mental health is the right idea. Building a more complex, ...

Currently, various classes of drugs are available for the treatment of mental illnesses - such as depression and anxiety disorders. However, although these drugs confer benefits, they are also ...

A novel target for using psilocybin to treat depression and anxiety without hallucinations has been identified. Psilocybin – the psychedelic compound that occurs naturally in certain ‘magic’ mushroom ...

An appetite-suppressing chemical also improves glucose tolerance and lowers insulin levels in obese and diabetic mice, researchers report in the November issue of Cell Metabolism, a publication of ...

WAUWATOSA, Wis. (CBS 58) -- A single drawing on a whiteboard inside a lab room at the Medical College of Wisconsin makes it easy to understand why researchers here believe psychedelics can effectively ...

UC Davis researchers have developed a new method that uses light to transform amino acids - the building blocks of proteins - into molecules that are similar in structure to psychedelics and mimic ...