Our understanding of protein synthesis has been conceptualised around the structure and function of the bacterial ribosome. This complex macromolecular machine is the target of important antimicrobial ...

Protein synthesis is a finely tuned process in the cell by macromolecules known as ribosomes. Which regulators are responsible for controlling protein synthesis in the brain, and how do they exert ...

Mitoribosomes of green algae display a great structural divergence from their tracheophyte relatives, with fragmentation of both rRNA and proteins as a defining feature. Here, we report a 2.9 Å ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But a critical aspect underlying the machinery of protein manufacture has long ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

A figure of the 80S ribosome structure. This image relates to an article that appeared in the Nov. 26, 2010, issue of Science, published by AAAS. The study, by Dr. Adam Ben-Shem at IGBMC (Institut de ...

An international team of scientists have used advanced microscopy to image how ribosomes recruit to mRNA. Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell ...

Most people carry the fungus Candida albicans on their bodies, without this causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat. Few ...

Led by Northwestern Engineering’s Michael Jewett, researchers created a new version of an engineered tethered ribosome dubbed Ribo-T, which provides a foundation to propel broad, new efforts in ...