However, there is marked heterogeneity in the methodology that makes direct comparison of these studies difficult. Such heterogeneity includes symptom definition (daily-to-monthly reflux symptoms; ...

Reflux disease manifests as acid regurgitation and heartburn and is a known risk factor for esophageal cancer. However, a new study now reports that the majority of patients do not have a higher risk ...

Gastroesophageal reflux disease (GERD) is a common condition in clinical practice, and results from the backward flow of stomach and duodenal contents into the esophagus and higher structures.

Long-term GERD, defined as five or more years, is the strongest risk factor for Barrett’s esophagus, a precursor to esophageal cancer. Additional risk factors include male gender, age over 50, obesity ...