A hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds back upon itself. Credit: Vossman/ ...
Parkinson's disease (PD) is a neurodegenerative disorder in which the α-synuclein protein abnormally aggregates within brain cells, causing neuronal damage. Through international collaboration, ...
CRISPR powers everything from gene editing to rapid diagnostics, but how did one of its most versatile branches arise? A new Cell study, “Functional RNA splitting drove the evolutionary emergence of ...
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The genome editing playbook is different in neurons and other nondividing cells, researchers discover
"Most people studying CRISPR have focused on dividing cells, but it turns out the rules of genome editing are different in nondividing cells like neurons," says Gokul Ramadoss, a Ph.D. candidate in ...
The CRISPR gene editing technique has had a dramatic influence on biomedical research, and has even been applied to a few humans to treat disease. Since its invention, scientists have improved, ...
A new genome editing tool—minimal versatile genetic perturbation technology (mvGPT)—can achieve simultaneous and orthogonal gene editing and gene regulation in human cells. The coming together of ...
Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...
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Can CRISPR cure HIV? Scientists say virus removed from cells in new research
Scientists are testing CRISPR gene editing as a potential HIV cure after successfully removing the virus from infected cells ...
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