*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...
As protein arrays have become increasingly consistent and reliable, more scientists have begun to incorporate them into their proteomics experiments. Researchers are attracted by the technology’s ...
The sequencing phase of the human genome project is now near completion, but then what? An even harder challenge remains — to identify the structures and functions of all proteins encoded in the ...
New Haven, Conn. — Yale University researcher Michael Snyder and his colleagues have created the first microchip able to analyze virtually all yeast proteins, the chemicals that carry out the ...
Until recently, protein–protein interactions (PPIs) were seen to present contact surfaces too broad and featureless to give newly developed PPI-modulating drugs much purchase. Developers of such drugs ...
Proteomics is the large-scale study of proteins, particularly their structures and functions. It involves the systematic identification, quantification, and analysis of the entire protein complement ...
Expression proteomics determines where and when proteins are expressed and measures their quantities. This qualitative and quantitative approach can compare protein expression across conditions, such ...