As language models learn to interpret words in a sentence, protein language models learn how amino acids work together within ...
For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and ...
The p53 tumor suppressor gene is the most frequently mutated gene in human cancers, and germ-line p53 mutations cause a familial predisposition for cancer. Germ-line or sporadic p53 mutations are ...
Some genome editing systems are highly conspicuous. They introduce double-strand breaks to DNA that attract the attention of cellular mechanisms such as nonhomologous end joining and homology-directed ...
Although previously thought to be neutral, research in yeast suggests that synonymous point mutations may have strongly nonneutral effects. A group of researchers from the University of Michigan (MI, ...
SNIPRs (Single-Nucleotide-Specific Programmable Riboregulators) can identify any RNA sequence based on a single nucleotide difference. [Shireen Dooling, Biodesign Institute, ASU] SNIPRs, easy-to-build ...
In a recent study posted to the medRxiv* pre-print server, Australian researchers comprehensively investigated the impact of 39 receptor-binding-domain (RBD) mutations in six severe acute respiratory ...
SAN DIEGO--(BUSINESS WIRE)--Turning Point Therapeutics, Inc., a clinical-stage precision oncology company designing and developing novel drugs to address treatment resistance, presented data from four ...
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