The coadministration of piperacillin-tazobactam and vancomycin may raise the risk for AKI, according to a warning from the US Food and Drug Administration. The ACORN trial included 2511 adults ...

In adults hospitalized with suspected sepsis, piperacillin-tazobactam was associated with a higher mortality rate and increased duration in organ dysfunction compared with cefepime, according to a ...

People believed to have sepsis who take piperacillin-tazobactam (Zosyn) and vancomycin have a 5% absolute mortality increase at 90 days compared with those who take cefepime and vancomycin, a new ...

BOSTON -- In adults hospitalized for acute infections, cefepime and piperacillin-tazobactam turned out to be equally safe in terms of serious kidney outcomes, although the latter antibiotic showed a ...

They found marked differences: treatment with piperacillin-tazobactam was associated with a 5 percent increase in 90-day mortality, more days on a ventilator, and more time with organ failure.

Researchers evaluated tolerance to piperacillin-tazobactam in 28 patients (mean age, 39.5 years; 50% women) who had immediate allergic reactions to amoxicillin between January 2023 and December 2024.

Researchers assessed the effects of different empiric antibiotic regimens on the risk for acute kidney injury among patients admitted to the intensive care unit. The risk for acute kidney injury was ...

About The Study: Among 2,511 adults hospitalized with acute infection, treatment with the antibiotic piperacillin-tazobactam did not increase the incidence of acute kidney injury or death in this ...