Because NF1 is an unpredictable disorder, it varies widely in severity – even among two people in the same family. Some people with NF1 may be completely unaware that they are affected, experiencing ...

It can spawn tumors throughout the nervous system and bone deformities that riddle the whole body with pain. One of the most common rare diseases in the world, the genetic condition neurofibromatosis ...

In mapping out future directions for NF1 research, the CABIN task force aims to bring about a “cycle of discovery, preclinical evaluation, and clinical translation.” Neurofibromatosis type 1 (NF1) is ...

I am writing this towards the end of August (2023) and would like to use this occasion to recognize a milestone: the 40th anniversary of my involvement in neurofibromatosis. On August 11, 1983, I sent ...

NF-1 is a genetic condition that causes brown skin patches, similar to birthmarks, and tumours 1. While the tumours are often benign, they can become cancerous over time and may cause a range of ...

The US Food and Drug Administration has approved mirdametinib for the treatment of neurofibromatosis type 1 (NF1) in adults and children. The drug, developed by SpringWorks Therapeutics, is the first ...

Most NF1-PNs cannot be fully removed with surgery or other treatments. Therefore, it’s important to take steps to manage the condition and reach out to others for support as you enter adulthood. Many ...