A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.

DNA origami sounds like science fiction, but for HIV vaccine researchers it is becoming a practical design tool. By folding strands of DNA into tiny three-dimensional scaffolds, scientists can arrange ...

Johns Hopkins engineers have created a new optical tool that could improve cancer imaging. Their approach, called SPECTRA, uses tiny nanoprobes that light up when they attach to aggressive cancer ...

A new vaccine design uses folded DNA to steer the immune system toward producing the rare immune cells needed to make protective antibodies against HIV.

Chemists present two studies that open up new possibilities for biotechnological applications. LMU chemists present two studies that open up new possibilities for biotechnological applications. In the ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, biosensing, DNA origami integrity reporting, and reusable mRNA detection through ...

To assemble these minuscule structures, researchers first create a scaffold: a long piece of single-stranded DNA with a carefully designed sequence of bases. Then they add hundreds of shorter DNA ...

According to the American Cancer Society, there will be an estimated 1,688,780 new cancer cases diagnosed and 600,920 cancer deaths in the U.S. in 2017. These numbers are stark and sobering, and worse ...

Previously, a similar approach to making biosensors was developed using a single DNA strand rather than a DNA origami structure. That earlier work was led by Kevin W. Plaxco (PhD '94) of UC Santa ...

LMU chemists present two studies that open up new possibilities for biotechnological applications. In the world of nanotechnology, the development of dynamic systems that respond to molecular signals ...