Rohit Ponnaiya breaks down his early Panthers vs. 49ers predictions ahead of Monday Night Football in Week 12. Free NFL picks ...

A former NFL star accused the Arizona Cardinals of point-shaving against the 49ers on Sunday after San Francisco cruised to a ...

Niners coach Kyle Shanahan announced Monday that veteran kicker Eddy Piñeiro suffered a Grade 1 strain in his right (kicking) ...

Call Sunday’s Niners-Cardinals showdown the Battle of Wounded Knee… and Leg, and Shoulder, and Feet, and even Appendixes. You ...

The San Francisco 49ers beat the Arizona Cardinals on Sunday at State Farm Stadium. How did it affect their standing heading into Week 12?

The 49ers (7-4) need three more wins to feel good about their playoff chances but a fourth should definitely secure a spot.

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

George Kittle had a surprise call from his wife while he was talking with reporters after the 49ers' win against the ...

Purdy guided the club to an impressive 41-22 win over the Arizona Cardinals that improved San Francisco to 7-4 this past ...

Carolina is coming off a huge emotional win over Atlanta, but a much tougher opponent is lurking next on the schedule.

San Francisco 49ers tight end George Kittle (85) catches a touchdown pass in front of Arizona Cardinals linebacker Akeem ...

Former Pro Bowl RB LeSean McCoy believes the Arizona Cardinals point shaved in their Week 11 loss to the San Francisco 49ers.