Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 23 (June 10, 2014), pp. 8649-8654 (6 pages) Ketamine is an NMDA receptor (NMDAR) antagonist that elicits ...

Early evidence links some Alzheimer’s Disease medications to small cognitive gains in children with autism and low IQ, ...

Memantine HCl 7mg, 14mg, 21mg, 28mg; ext-rel caps. Memantine is postulated to exert its therapeutic effect through its action as a low to moderate affinity uncompetitive (open-channel) N-methyl ...

A new Cochrane review casts doubt on the value of ketamine and other N-methyl-D-aspartate (NMDA) receptor agonists to relieve chronic noncancer pain. “Clinicians should know that there is currently no ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

D epression can be challenging to treat. Typical antidepressants, which affect levels of chemicals in the brain involved in mood regulation, have been evolving for decades. But recent findings ...

Despite growing off-label use, ketamine and related NMDA blockers show no reliable evidence of easing chronic pain, highlighting the urgent need for safer and more effective treatments. Review: ...

SAGE-718, a positive allosteric modulator (PAM) of NMDA receptor activity, improved mean scores on five standard memory tests in 26 Alzheimer's patients with mild cognitive deficits, reported Aaron ...

relationship between anti-NMDA receptor encephalitis and vaccination (or tumors). In addition, it is worth mentioning that HPV can cause cancers, and anti-NMDA receptor encephalitis is associated with ...