Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, ...

Iron metabolism imbalance and ferroptosis are central to PF pathogenesis, offering new therapeutic targets. Ferroptosis links oxidative stress, iron overload, and fibrotic remodeling, affecting key ...

Cell-cell interactions via proteins and ligand-receptor interactions contribute to PF pathogenesis. Single-cell RNA genome sequencing technique and bio-informatics oriented approaches combined with ...

Credit: Getty Images. The first step in diagnosing idiopathic pulmonary fibrosis is ruling out other known causes of interstitial lung disease. Making an accurate diagnosis of IPF is critical because ...

Acute lung injury (ALI) is a critical clinical condition characterized by diffuse inflammation of the lung parenchyma and ...

Treatment with elexacaftor-tezacaftor-ivacaftor is associated with reduced levels of systemic inflammatory markers, which correlate with improved lung function in patients with cystic fibrosis.

Cystic fibrosis (CF) and pulmonary fibrosis (PF) are two chronic conditions that damage the lungs. Treatment for both aims to improve breathing, manage symptoms, and prevent further lung damage. Your ...

The COVID-19 pandemic engulfed the U.S. five years ago this month, leaving not only lingering mental health effects but also long-term physical symptoms. One of those included a condition known as ...

A CRISPR gene-editing therapy has the potential to offer an effective, long-lasting treatment for cystic fibrosis after overcoming a major challenge that held back previous genetic therapies. The ...