Panelists discuss how idiopathic pulmonary fibrosis (IPF), a progressive and often fatal interstitial lung disease, presents significant clinical challenges due to its variable trajectory, limited ...

Iron metabolism imbalance and ferroptosis are central to PF pathogenesis, offering new therapeutic targets. Ferroptosis links oxidative stress, iron overload, and fibrotic remodeling, affecting key ...

Pulmonary fibrosis (PF) is a fatal lung disease characterized by excessive deposition of extracellular matrix proteins in the lung interstitium due to excessive fibroblast activation, which leads to ...

Pulmonary fibrosis is a progressive interstitial lung disease characterized by excessive extracellular matrix deposition, architectural distortion and declining lung function. While epithelial injury ...

Credit: Getty Images. The first step in diagnosing idiopathic pulmonary fibrosis is ruling out other known causes of interstitial lung disease. Making an accurate diagnosis of IPF is critical because ...

Pulmonary fibrosis—also known in technical terms as idiopathic pulmonary fibrosis (IPF)—is a rare but life-threatening disease. It causes scarring of the connective tissue between the functional ...

Chronic lung inflammation in cystic fibrosis (CF) often persists even after treatment with newly-approved gene therapies or small molecule CFTR modulators—an unresolved clinical paradox. A new study ...

First-time lung transplants in patients with CF significantly decreased after ETI became available, while retransplants were largely unaffected.