We cloned full-length KAI1 cDNA cloned into the yeast vector pEG202-NLS (Origene Technologies) as bait, and performed yeast two-hybrid screening and mating assay according to the manufacturer's ...

Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma. We found that 109 patients (63.4%) had MRP-1-positive ...

Scientists, using a mouse model, have uncovered a novel protein interaction that promotes the spread of cancer cells (a process known as metastasis) in a class of tumors collectively called sarcomas.

Altered expression of the KAI1 metastasis suppressor gene (Dong et al., 1995) in a wide range of human tumours is now well established (reviewed in Jackson and Marreiros, 2004). However, the ...

Fluorouracil Modulation in Colorectal Cancer: Lack of Improvement With N -Phosphonoacetyl- l -Aspartic Acid or Oral Leucovorin or Interferon, But Enhanced Therapeutic Index With Weekly 24-Hour ...