Villification of the intestinal epithelium is driven by Foxl1 through activation of PDGFRα and BMPs
The primitive gut tube of mammals initially forms as a simple cylinder consisting of the endoderm-derived, pseudostratified epithelium and the mesoderm-derived surrounding mesenchyme. During ...
The intestine is an important organ involved in digestion, absorption, and energy metabolic regulation such as appetite regulation and nutrient accumulation through various intestinal hormones 1.
Intestinal cells can change specializations during their lives. The BMP signaling pathway—an important communication mechanism between cells—appears to be the driver of these changes. That is what ...
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