This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Inspired by hibernating squirrels, scientists have developed a promising new drug that could transform how we treat heart ...

Adults with heart failure with reduced ejection fraction (HFrEF) who took a "polypill" combining medications prescribed for ...

Trial data show FX45 may help improve heart function in people with pulmonary hypertension and heart failure with reduced ejection fraction.

An international team of researchers has discovered a natural mechanism that protects the heart from heart failure with preserved ejection fraction (HFpEF), a serious condition in need of effective ...

Adults with heart failure with reduced ejection fraction (HFrEF) who took a "polypill" combining medications prescribed for the treatment of heart failure, had improved heart function and symptoms, ...

After years of searching for a therapy to combat heart failure with preserved ejection fraction, a research team may have found a breakthrough candidate. Their drug not only improved heart function in ...