St. Jude Children's Research Hospital scientists have uncovered a regulatory mechanism for signaling of Sonic Hedgehog (SHH), a pathway essential for embryonic development. The findings, published in ...

The Hedgehog (Hh) signalling pathway is a highly conserved mechanism that directs cell fate, patterning and tissue homeostasis throughout embryogenesis and adult life. Signalling is initiated when a ...

A discovery with major implications for cancer treatment has been made by a team of researchers from Rensselaer Polytechnic Institute (RPI), the University of Nebraska Medical Center (UNMC), ...

Cells need to communicate with each other in order to develop properly, and this process is called cell signaling. The interest of the Hoogendoorn group is the Hedgehog signaling pathway, which is ess ...

Age-associated mutation patterns and a potential therapeutic opportunity in early-onset colorectal cancer. This is an ASCO Meeting Abstract from the 2026 ASCO Gastrointestinal Cancers Symposium. This ...