Genome-wide analysis reveals host–virus genetic interactions in cancer risk

A study from Columbia University Mailman School of Public Health reports a major advance in understanding how interactions ...
The University of Alabama at Birmingham

Why some organ transplants trigger harmful antibody responses

UAB researchers discover that the immune system consistently targets the same region of mismatched HLA proteins after organ ...
The American Journal of Managed Care

Study Suggests Genetic Link Between HLA Alleles, MG

Two human leukocyte antigen (HLA) alleles, DRB1*04.04 and DRB1*03, show a significant correlation with myasthenia gravis (MG) prevalence. Northern Europe exhibits the highest prevalence of MG and ...
Mirage News

Research Links Host-Virus Genes to Cancer Risk

A study from Columbia University Mailman School of Public Health reports a major advance in understanding how interactions between human and viral ...
ascopubs.org

Assessment of Functional Status of Human Leukocyte Antigen Class I Genes in Cancer Tissues in the Context of Personalized Neoantigen Peptide Vaccine Immunotherapy

Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...