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A new paper published this week in the journal Nature describes how researchers pieced together the entire molecular structure of the protein shell of the HIV virus using GPU-based simulations ...
Human immunodeficiency virus type 1 (HIV-1) targets important cells of our immune system, making infected individuals more ...
Research by a multi-institutional team, including two members from the University of Delaware, has revealed new details about the HIV virus capsid structure and how it develops. A capsid is a protein ...
In the ongoing fight against HIV, scientists have taken a new step toward long-term control of the virus. Researchers have ...
Stopping a virus from maturing As the HIV virus develops, a cascade of events occurs, affecting its structure and ability to infect. Think of the TV cooking show “Chopped.” But in this case, protein ...
According to the study, hitting HIV’s Achilles heel may require leveraging the “social network” that governs the virus’ structure.
In a discovery that could spur the development of new therapies for more than 40 million HIV patients worldwide, scientists from Rutgers University and the Salk Institute determined the molecular ...
The matrix shell of the HIV-1 virus may have a different shape than previously thought, and a newly proposed model has significant implications for understanding how the virus functions.
Scientists have determined the molecular structure of HIV Pol, a protein that plays a key role in the late stages of HIV replication, or the process through which the virus propagates itself and ...
By exploiting the capsid’s structure, researchers theoretically could deliver a molecular padlock that prevents the viral core from opening and the virus from spreading.
Scientists use pore-forming toxin to punch holes in the membrane of HIV virus-like particles, making the capsid accessible to external cell factors and small molecules.