The resulting complex of viral cDNA and virion proteins, now referred to as the pre-integration complex (PIC), is transported to the nucleus (Fig. 1). Figure 1: Models of flap-dependent HIV ...
Enhancement of HIV-1 Infectivity. Early work on this topic ... protein other than CD4 that blocks the function of Env in the virion. Nef enhances infectivity by downregulating this unknown protein ...
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