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How chromosomes shape up for cell division: Scientists reveal DNA loop formation mechanisms
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...
For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...
The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...
MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...
New findings shed light on how chromosomes manage the various pushing and pulling forces generated when cells divide. Specifically, researchers show that chromosomes resist being punctured by the ...
Japanese researchers report a new ion detector, MARIO. Using it, they show that changes in the intracellular concentration of free magnesium ions (Mg 2+) is critical for the chromosome folding that ...
Scientists studying zebrafish larvae noticed something weird. Skin cells seemed to be dividing without replicating their DNA. They confirmed that what they were seeing was real, upending what we ...
Scientists at the Ruđer Bošković Institute (RBI) in Zagreb, Croatia, have discovered that the protein CENP-E, long believed to act as a motor dragging chromosomes into place during cell division, in ...
A research team from the University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered ...
As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...
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How Chromosomes Shape Up for Cell Division
Among the many marvels of life is the cell’s ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...
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