Peering through his microscope in 1910, Franco-Canadian microbiologist Félix d'Hérelle noticed some "clear spots" in his bacterial cultures, an anomaly that turned out to be viruses preying on the ...

In promising experiments, phage therapy forces bacteria into a no-win dilemma that lowers their defenses against drugs they’d evolved to withstand. By Patience Asanga / Knowable Magazine Published Sep ...

Multidrug resistance in Gram-negative bacteria represents a major public health challenge, with these organisms evolving a myriad of mechanisms to evade the effects of antibiotic treatment. One ...

Peering through his microscope in 1910, the Franco-Canadian microbiologist Félix d’Hérelle noticed some “clear spots” in his bacterial cultures, an anomaly that turned out to be viruses preying on the ...

Researchers have described a new class of molecules that inhibit efflux pumps so that antiboitics remain effective. The World Health Organization has labeled antimicrobial resistance a global threat ...

Besides their normal role, pump overexpression confers drug resistance. Knowing the structure is a step to disabling the pumps with inhibitors BIRMINGHAM, Ala. – Tuberculosis is the world’s leading ...

This is a preview. Log in through your library . Abstract Antibiotic resistance is often the result of mutations that block drug activity; however, bacteria also evade antibiotics by transiently ...

University of Colorado has divulged efflux pump (bacterial) inhibitors reported to be useful for the treatment of bacterial infections, particularly, gram-negative bacterial infections.

A very alarming link between agricultural glyphosate weed killer use and multidrug antibiotic resistance in nosocomial ...

AMES, Iowa – Research teams led by Edward Yu of Iowa State University and the Ames Laboratory have described the structures of two proteins they believe pump antibiotics from bacteria, allowing the ...