Retroviruses are the causative agents of serious diseases, such as acquired immunodeficiency syndromes and several cancers, and are also useful gene therapy vectors. Retroviruses contain two ...

Myc is a transcriptional regulator of the basic helix-loop-helix leucine zipper protein family. It has strong oncogenic potential, mutated or virally transduced forms of Myc induce lymphoid tumors in ...

What is dimerization? It is a process where two molecules of similar chemical composition come together to form a single polymer known as a dimer. Where does dimerization occur? It happens throughout ...

DNA-Repair Gene Polymorphisms Predict Favorable Clinical Outcome Among Patients With Advanced Squamous Cell Carcinoma of the Head and Neck Treated With Cisplatin-Based Induction Chemotherapy Median ...

Although class A G protein–coupled receptors (GPCRs) can function as monomers, many of them form dimers and oligomers, but the mechanisms and functional relevance of such oligomerization is ill ...

Dimerization of the human neuropeptides oxytocin and vasopressin can produce new types of bioactive molecules. Such new constructs provide several opportunities to optimize the efficacy of these ...

Cell surface receptors, such as the G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK), play central roles signalling pathways. Due to their central role in regulating a wide range ...

Cutaneous Lymphomas Reported to the National Cancer Institute's Surveillance, Epidemiology, and End Results Program: Applying the New WHO–European Organisation for Research and Treatment of Cancer ...

Please provide your email address to receive an email when new articles are posted on . CHICAGO — In this Healio Video Perspective from Eyecelerator@AAO, Michel Dahan, CEO of Alkeus Pharmaceuticals ...

Merck Sharp & Dohme LLC has identified targeted activator of cell kill (TACK) compounds acting as Gag polyprotein (HIV-1)/protein Pol dimerization inducers reported to be useful for the treatment of ...

Preparation methods have a large influence on the folding and oligomerization behaviour of proteins in solution. In an experiment carried out by Anton Paar, bovine serum albumin (BSA) dissolved in ...