CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises unfold in real time. Inside every cell, DNA breaks, repairs, and sometimes ...

This footage shows the fluorescent sensors in action inside a living cell. They appear as bright green spots the moment they bind to sites of DNA damage. Cancer research, drug safety testing and ...

A new sensor lets scientists watch DNA repair itself in living cells without disrupting natural processes. The novel fluorescent sensor, developed at Utrecht University, has the potential to ...

The 2024 Albert Lasker Award for Basic Medical Research is awarded to Zhijian (James) Chen for his landmark discoveries that explain how DNA stimulates immune responses. DNA is best known as genetic ...

Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage ...

Drawing inspiration from natural cell signaling cascades, chemists at Université de Montréal (UdeM) have developed a DNA-based signaling cascade that allows them to quantify and report via an easily ...

Today (September 19), the Lasker Foundation announced this year’s winners of the Lasker Awards. Zhijian “James” Chen, a biochemist at the University of Texas Southwestern Medical Center, was awarded ...

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked. Epigenetic modifications can act as on-off ...

A new fluorescent sensor lets scientists track DNA damage and repair in real time inside living cells, advancing cancer research, drug testing and ageing biology. (Nanowerk News) Cancer research, drug ...