Nanobody repairs misfolded CFTR inside cells, boosting function in cystic fibrosis

A tiny antibody component could fundamentally transform the treatment of cystic fibrosis: For the first time, researchers ...
The Boston Globe

Vertex reports an earnings miss and pause on cystic fibrosis trial

Vertex Pharmaceuticals on Monday reported disappointing first-quarter earnings impacted by weaker-than-expected sales of its drugs for cystic fibrosis, and little or no contributions from a gene ...
Healio

Cystic fibrosis triple therapy improves lung ventilation, morphology in children

Please provide your email address to receive an email when new articles are posted on . Lung clearance index improved in month 3 and 12 of elexacaftor/tezacaftor ...
EurekAlert!

A fundamentally new therapeutic approach to cystic fibrosis: Nanobody repairs cellular defect

A tiny antibody component could fundamentally transform the treatment of cystic fibrosis: For the first time, researchers ...
Healio

Cystic fibrosis triple therapy improves clinical outcomes in N1303K mutation

Please provide your email address to receive an email when new articles are posted on . Sweat chloride did not significantly differ between baseline and day 28 of triple therapy in this patient ...
Yahoo

‘Life-changing’ therapy now available for cystic fibrosis patients

Hundreds of people with cystic fibrosis are to be offered a new pill which has been hailed as “life changing” by health experts. Modulator drugs work by helping to make the CFTR protein work ...
Monthly Prescribing Reference

Inhalation Therapy Fast Tracked for Cystic Fibrosis With a Specific Mutation

SPL84 is administered directly into the lungs where it is taken up by the cells and is expected to drive the production of fully functional CFTR proteins. The Food and Drug Administration (FDA) has ...
Medscape

Triple Therapy Boosts Glycemic Control in Cystic Fibrosis

Researchers conducted a phase 3b open-label trial at multiple sites in Australia and the European Union to assess the effect of elexacaftor-tezacaftor-ivacaftor, an approved medication for cystic ...
MedPage Today

Phage Therapy Promising in Multi-Drug Resistant Infections in Cystic Fibrosis

Bacteriophages (phages) are viruses that kill bacteria. Phage therapy used as an experimental therapy in 51 cystic fibrosis patients with multi-drug resistant infections showed that most had a ...
Business Wire

Cystic Fibrosis Foundation Commits Up to an Additional $24 Million for Prime Medicine to Develop Gene Editing Therapy

BETHESDA, Md.--(BUSINESS WIRE)--Today, the Cystic Fibrosis Foundation announced an additional investment of up to $24 million in Prime Medicine to continue the development of a gene editing therapy ...
News Medical

Phage therapy could offer safe and effective treatment option for Cystic Fibrosis lung infections

Scientists from the University of Liverpool have shown that phage therapy could offer a safe and effective alternative to antibiotics in the treatment of Cystic Fibrosis lung infections. Chronic lung ...
Medscape

Gene Therapy for Cystic Fibrosis Improves Lung Function

Monthly administration of liposome-delivered gene therapy for cystic fibrosis (CF) improved forced expiratory volume (FEV) in a randomized, double-blinded, placebo-controlled phase 2b clinical trial.