This article was originally published by Dome in its January/February 2024 issue. Early in her career, Johns Hopkins physician-scientist Eileen Scully began to explore ways that viral infections such ...

A study published on Sept. 17 in PLOS Pathogens reports results from a clinical trial of an histone deacetylases (HDAC) inhibitor that had shown potential in preclinical studies and answers open ...

A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them. The findings highlight how close -- yet still far ...

Due to the 4-hour maturation half-life of the Timer protein's blue-to-red chromophore, we can detect reactivated or recently silenced proviruses with high sensitivity using Timer fluorescence.

During replication and transmission of HIV (green), RNA is converted to DNA. With the CDC urging screening for all willing patients, providers will be testing and managing a growing number of ...

Dynamic Contrast-Enhanced Magnetic Resonance Imaging As a Biomarker for the Pharmacological Response of PTK787/ZK 222584, an Inhibitor of the Vascular Endothelial Growth Factor Receptor Tyrosine ...

You may develop flu-like symptoms like chills and fever if you have acute HIV infection. During the clinical latency stage, HIV typically does not cause any symptoms. The only way to know if you have ...