Most gene-editing tools are blind to context. Point them at a DNA sequence and they cut, whether that sequence sits inside a ...
CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a precision tool, but is not perfect, and misplaced DNA edits can compromise ...
CRISPR-Cas9 has the reputation for being “snip happy,” for cutting and cutting a genomic site until one of the cell’s DNA repair systems finally skips a beat, leaving the site imperfectly ...
The CRISPR system, which involves a Cas enzyme to cut DNA, is a powerful tool for gene editing. But the genetic scissors sometimes make changes at the wrong place, creating a major safety problem that ...
CRISPR-based gene editing just got safer with the design of a new SuperFi-Cas9 variant that more readily discriminates against mismatches and retains the accuracy and speed of naturally occurring Cas9 ...