Through non-negative matrix factorization (NMF) cluster analysis on 131 training samples, we identified four molecular subtypes for HR + /HER2 + breast cancer: MUKDEN I (n = 41), MUKDEN II (n = 38), ...
Current breast cancer classification methods, particularly immunohistochemistry and PAM50, face challenges in accurately characterizing the HER2-low subtype, a therapeutically relevant entity with ...
Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the patient will experience a recurrence years after their initial diagnosis. Now, ...
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