A new MD Anderson study finds that pre-existing immune rejection and the intrinsic fitness of donor-derived CAR T cells ...
Despite the remarkable clinical efficacy of chimeric antigen receptor (CAR) T cells in hematological malignancies, only a subset of patients achieve a durable complete response. Furthermore, ...
Cold Spring Harbor Laboratory researchers found that activating the transcription factor PPARD in immune cells, including CAR T cells, boosts their metabolic fitness and slows colorectal and other ...
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