Antinuclear antibodies (ANAs) are detected in the serum of patients with most systemic autoimmune diseases. The traditional tool used to detect ANAs is indirect immunofluorescence. A new, automated ...

Autoimmune rheumatic diseases (ARDs) represent a diverse group of conditions in which the immune system mistakenly targets the body’s own tissues, often affecting the musculoskeletal system and ...

Expert Rev Mol Diagn. 2012;12(1):65-74. The NE is composed of three morphologically and functionally interconnected structures: a double bilayer nuclear membrane enclosing the perinuclear space; the ...

A new approach targets the B-cell pathway with bispecific antibodies, building on decades of research that establishes the role of B cells and self-reactive antibodies in lupus, systemic sclerosis, ...

On June 13, 2022, the biotechnology company Thermo Fisher Scientific Inc. announced that its two new diagnostic blood tests – one for lupus and one for systemic sclerosis – were approved by the U.S.

Stress isn’t usually the direct cause of a positive ANA test, but it can influence the immune system, potentially exacerbating symptoms in those with autoimmune disorders. If you have symptoms like ...

A very small number of people who test negative for antinuclear antibody (ANA) in the blood, which is a sign of the most common type of lupus, still have the condition. Lupus is an autoimmune disease ...

An international research group directed by UMC Utrecht has developed and characterized two first-in-class antibodies that specifically block the high-affinity IgG receptor FcγRI. Their findings open ...

If a person experiences joint pain and tests positive for an antinuclear antibody (ANA) test, this may suggest the presence of an underlying condition causing joint problems and discomfort. An ANA ...

Sjögren’s diseaseis an autoimmune disease that primarily affects women and often goes undetected for years. In today’s Daily Dose, Dr. Lacy Anderson takes a closer look at Sjögren’s disease, including ...

Blood tests can help with the diagnosis of autoimmune hepatitis. These include tests for increased liver enzymes or antibody levels. However, other tests are necessary to confirm the diagnosis.