Addex Shareholders Approve All Resolutions at Annual General Meeting

Ad Hoc Announcement Pursuant to Art. 53 LR Geneva, Switzerland, June 30, 2026 - Addex Therapeutics (SIX and Nasdaq: ADXN), a ...

Gain Therapeutics Receives FDA Clearance of IND to Advance GT-02287 into Phase 2 Clinical Development for Parkinson’s Disease

IND authorization paves the way for initiation of GT-02287 Phase 2 clinical development in the U.S., expected during 3Q26FDA’s decision follows ...
Nasdaq

Bionomics Announces Update on the α7 Nicotinic Acetylcholine Receptor (nAChR) Positive Allosteric Modulator (PAM) Collaboration with MSD

ADELAIDE, Australia, and CAMBRIDGE, Mass., Sept. 14, 2023 (GLOBE NEWSWIRE) -- Bionomics Limited (Nasdaq: BNOX) (Bionomics or Company), a clinical-stage biotechnology company developing novel, first-in ...

Addex Therapeutics Reports First Quarter 2026 Financial Results and Provides Corporate Update

Ad Hoc Announcement Pursuant to Art. 53 LRGeneva, Switzerland, June 25, 2026-Addex Therapeutics (SIX and Nasdaq: ADXN), a clinical-stage ...
TMCnet

Addex Therapeutics to Report 2026 First Quarter Financial Results and Host Conference Call on June 25, 2026

Title: Addex Therapeutics Reports Q1 2026 Financial Results and Provides Corporate Update Date: June 25, 2026 Time: 16:00 CET ...
Nature

Development of an allosteric adhesion GPCR nanobody with therapeutic potential

Allosteric modulation of receptor responses to endogenous agonists has therapeutic value, maintaining ligand profiles, reducing side effects and restoring mutant responses. Adhesion G-protein-coupled ...
News Medical

Targeting neuroinflammation with C5aR1 negative allosteric modulators

This article and associated images are based on a poster originally authored by Kamini Magon, Alison Holiday, Iwona Ziomkiewicz, Jonathan Powell, Jon Dunn, David Tickle, David Dexter, Janusz ...
Phys.org

How a tryptophan-rich allosteric communication network helps activate a major drug target receptor

The study also clarifies the functional role of the receptor's conserved sodium-binding pocket, showing that sodium egress strongly promotes activation-related conformational states, including a ...
BioWorld

Sage Therapeutics discovers new GluN2A negative allosteric modulators

Sage Therapeutics Inc. has described sterol derivatives acting as glutamate receptor ionotropic, NMDA 2A (GRIN2A; GluN2A) negative allosteric modulators reported to be useful for the treatment of ...
Nature

Intracellular GPCR modulators enable precision pharmacology

G-protein-coupled receptors (GPCRs) are a large and diverse family of cell surface receptors that play critical roles in transmitting extracellular signals to the interior of the cell. GPCRs represent ...
Healio

Allosteric modulator nonsuperior to placebo in Parkinson’s disease

Please provide your email address to receive an email when new articles are posted on . Change from baseline in gait variability did not differ between groups, regardless of cognitive load. Treatment ...
BioWorld

Sage Therapeutics divulges new GluN2A negative allosteric modulators

Sage Therapeutics Inc. has synthesized sterol derivatives acting as glutamate receptor ionotropic, NMDA 2A (GRIN2A; GluN2A) negative allosteric modulators reported to be useful for the treatment of ...