The cellular and molecular mechanisms that lend AJs this versatility are not well understood, but the actin motor, myosin II, has previously been implicated in AJ assembly and function 1. Now, on page ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...

Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to be closed or chase down bacteria in the bloodstream. This mobility is ...

The inner cortex of eukaryotic cells is largely composed of the protein actin, organized in a filamentous network that forms the cytoskeleton. The actin cytoskeleton plays major roles in cellular ...

Point mutations in vascular smooth muscle α-actin (SM α-actin), encoded by the gene ACTA2, are the most prevalent cause of familial thoracic aortic aneurysms and dissections (TAAD). Here, we provide ...

Cell generated force plays essential roles in a wide range of biological processes, such as cell motility, cytokinesis, and tissue morphogenesis. In a study published in Nature Communications, a ...

This is a preview. Log in through your library . Abstract Acanthamoeba myosin-I bound to substrates of nitrocellulose or planar lipid membranes on glass moved actin filaments at an average velocity of ...